Genus Senna belongs to the family of Fabaceae and comprises of about 250–300 accepted species extensively dispersed in tropical and subtropical regions. The Senna species is widely used in Africa, Asia, Europe and Latin America, some Senna species are well-known for their antimicrobial and anti-inflammatory activities with basis in traditional medicine to treat diabetes, microbial infections, malaria fever and other ailments. This review was extensively prepared by a comprehensive assessment of available literature via major scientific catalogues. The genus contains important metabolites such as alkaloids, anthraquinones, flavonoids, tannins, glycosides, steroids, terpenoids, saponins and volatile oils. The crude extracts and isolated metabolites from Senna displayed a wide range of in vitro and in vivo pharmacological activities such as antidiabetic, anti-gonorrhea, antimicrobial, antioxidant, antipyretic, antinociceptive, antidepressant and anti-inflammatory functions displayed by the genus Senna. The objective of this review is to critically explore the advances in the botanical, phytochemical, pharmacological and toxicological studies of the genus Senna, which will provide a useful bibliography for further investigations and applications in medicines. The review reveals that Senna species have been widely used for therapeutic purpose and substantial traditional evidence of their applications exist. Further studies should be tailored towards targeting active metabolites responsible for the pharmacological activities, structural elucidation and toxicological appraisals.

属塞纳属于豆科（Fabaceae）的，并且包括的广泛分散在热带和亚热带地区约250-300接受物种。在塞纳种被广泛使用在非洲，亚洲，欧洲和拉丁美洲，一些塞纳物种是它们与传统医学治疗糖尿病，微生物感染，疟疾发热等疾病基础的抗菌和抗炎活性知名。本综述是通过主要科学目录对可用文献的全面评估而广泛准备的。该属包含重要的代谢产物，如生物碱，蒽醌，类黄酮，单宁，糖苷，类固醇，萜类，皂苷和挥发油。粗提物和分离出的代谢物番泻叶显示了广泛的体外和体内的药理活性，如抗糖尿病药，抗淋病，抗微生物剂，抗氧化剂，解热，镇痛药，抗抑郁药和抗炎功能由显示属番泻叶。这篇综述的目的是批判性地探索塞纳属的植物学，植物化学，药理学和毒理学研究的进展，这将为进一步研究和在医学中的应用提供有用的参考书目。审查显示塞纳该物种已被广泛用于治疗目的，并且存在其应用的大量传统证据。应该针对进一步的研究进行量身定制，以靶向负责药理活性，结构解析和毒理学评估的活性代谢物。