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Development of anisotropic ferromagnetic composites for low-frequency induction heating technology in medical applications
Materials Today Chemistry ( IF 6.7 ) Pub Date : 2020-12-24 , DOI: 10.1016/j.mtchem.2020.100395
Z. Xiang , M.Q. Le , P.-J. Cottinet , P. Griffiths , G.P. Baeza , J.-F. Capsal , P. Lermusiaux , N. Della Schiava , B. Ducharne

Modern medical applications such as varicose treatment, hyperthermia, or even endovenous thermal ablation require to bring heat flux locally through the human body. The challenge behind such techniques resides in converting electrical power into heat flux and transfer it directly to the targeted area without contaminating and damaging the surrounding tissues. Low-frequency induction heating (LFIH) of catheters made out of biocompatible magnetic composites is an elegant solution. By inserting the catheter through the varicose to be treated and by exciting it through LFIH, it seems possible to reach a temperature high enough to properly heal the damaged area while preserving the surrounding healthy ones. Although recent published results seem promising, an optimized procedure is still required to achieve further improvements. Many directions lying on the active material formulation have been largely explored in the past (variations of particle content, nature, size, and shape). In this work, we propose an alternative solution, which involves the processing of ferromagnetic composites under a constant homogeneous magnetic field, leading to the strong anisotropic behavior due to particles alignment. Remarkably, experimental results demonstrate that by exciting such anisotropic composites along the alignment direction enhances the LFIH effect by more than 30%. Moreover, improvements can also be noticed in the perpendicular direction, meaning that the structured distribution is enough to increase the ferromagnetic properties. Furthermore, the resulting composite is highly flexible, making it easier to be integrated in several medical devices (e.g. endovenous thermal catheter, electromagnetic tracking system, and so on).



中文翻译:

用于医疗领域的低频感应加热技术的各向异性铁磁复合材料的开发

现代医学应用,例如静脉曲张治疗,体温过高甚至静脉热消融,都需要使热​​通量局部穿过人体。这种技术背后的挑战在于将电能转换成热通量并将其直接传递到目标区域,而不会污染和损坏周围的组织。由生物相容性磁性复合材料制成的导管的低频感应加热(LFIH)是一种出色的解决方案。通过将导管插入要治疗的静脉曲张并通过LFIH激发,似乎可以达到足够高的温度以适当治愈受损部位,同时保留周围的健康部位。尽管最近发表的结果似乎很有希望,但仍需要优化的程序来实现进一步的改进。过去已经对活性材料配方的许多方向进行了广泛探索(颗粒含量,性质,大小和形状的变化)。在这项工作中,我们提出了一种替代解决方案,其中涉及在恒定的均匀磁场下处理铁磁复合材料,由于粒子排列而导致强各向异性行为。值得注意的是,实验结果表明,通过沿取向方向激发此类各向异性复合材料,可使LFIH效应提高30%以上。此外,还可以在垂直方向上注意到改进,这意味着结构化分布足以增加铁磁性能。此外,所得复合材料具有很高的柔韧性,使其更易于集成到多种医疗设备中(例如

更新日期:2020-12-24
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