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Pilot of a novel theoretically derived intervention for cancer-related anxiety with patients with advanced or recurred disease
Behavioural and Cognitive Psychotherapy ( IF 2.0 ) Pub Date : 2020-10-01 , DOI: 10.1017/s1352465820000697
Leah Curran , Louise Sharpe , Phyllis Butow

Background:Treatments for cancer-related anxiety show modest benefits, but most have been trialled in patients with early stage disease or patients who are currently disease free. However, many patients with cancer have incurable disease, or their disease is slowly progressing or likely to recur. Treating anxiety in the context of realistic threat and ongoing uncertainty is particularly challenging. Based on a theoretical model of cancer-related anxiety, we developed a transdiagnostic intervention for patients with advanced or recurred disease who are experiencing clinically significant anxieties. The intervention was a novel integration of traditional and contemporary CBT.Aims:To evaluate the feasibility, acceptability and preliminary efficacy of the intervention in a pilot with patients with advanced or recurred cancer.Method:Twelve patients with advanced or recurred cancer, who were experiencing anxiety, participated. Feasibility and acceptability were assessed with participant’s ratings and adherence and retention rates. Psychological outcomes (anxiety, traumatic symptoms, fear of progression, depression, death anxiety and quality of life) were assessed pre-intervention, post-intervention and at 2-month follow-up.Results:Eleven of the 12 participants completed at least five therapy sessions of whom eight completed all nine sessions. Participants rated the intervention as having excellent face validity. Post-intervention, statistically significant improvements were demonstrated for anxiety, traumatic symptoms, fear of progression, depression and quality of life. These improvements were maintained at follow-up for anxiety, traumatic symptoms and depression.Conclusions:This pilot provides preliminary evidence for the feasibility, acceptability and effectiveness of the novel intervention for cancer-related anxiety in the context of advanced disease.

中文翻译:

对晚期或复发性疾病患者的癌症相关焦虑进行新的理论衍生干预试点

背景:癌症相关焦虑的治疗显示出适度的益处,但大多数已在早期疾病患者或目前无病患者中进行了试验。然而,许多癌症患者患有无法治愈的疾病,或者他们的疾病进展缓慢或可能复发。在现实威胁和持续不确定性的背景下治疗焦虑尤其具有挑战性。基于癌症相关焦虑的理论模型,我们为患有临床显着焦虑的晚期或复发性疾病患者开发了一种跨诊断干预措施。该干预是传统和现代 CBT 的一种新颖整合。目的:评估干预在晚期或复发性癌症患者试点中的可行性、可接受性和初步疗效。方法:12 名患有焦虑症的晚期或复发性癌症患者参加了研究。可行性和可接受性通过参与者的评分以及坚持和保留率进行评估。在干预前、干预后和 2 个月的随访中评估心理结果(焦虑、创伤症状、对进展的恐惧、抑郁、死亡焦虑和生活质量)。结果:12 名参与者中有 11 人完成了至少 5其中八人完成了所有九次治疗。参与者将干预评为具有出色的面部效度。干预后,焦虑、创伤症状、对进展的恐惧、抑郁和生活质量显示出统计学上的显着改善。这些改善在焦虑、创伤症状和抑郁的随访中得以保持。结论:
更新日期:2020-10-01
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