Background

Bipolar disorder (BP) is highly comorbid with obesity, however, little is known about how BP might be associated with bariatric surgery outcomes.

Methods

In this retrospective clinical cohort study, 1034 patients completed a psychological evaluation, and screening positive for possible BP was defined as a score ≥7 and moderate disability on the Mood Disorders Questionnaire. Food addiction (FA), subthreshold binge eating disorder (BED), and illegal drug use were also assessed using standardized questionnaires.

Results

The 54 (5.2%) patients screening positive for BP were less likely to have bariatric surgery compared to 980 (94.8%) patients who screened negative for BP (5 patients or 9.3% vs 273 patients, or 27.9%). Patients with possible BP also had significantly higher prevalence of FA (37% vs 13.2%), subthreshold BED (29.6% vs 8.3%) and illegal drug use (7.4% vs 2.1%).

Conclusions

In this retrospective clinical cohort study, patients who screened positive for BP had a higher prevalence of food addiction, subthreshold binge eating disorder and recent illegal drug use. They also demonstrated lower completion rates for having bariatric surgery. Clearly, more needs to be learned about how to help patients with symptoms of bipolar disorder manage their obesity and behavioral challenges.

中文翻译：

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躁郁症的症状与减肥手术完成率较低和食物成瘾较高有关

背景

双相情感障碍（BP）与肥胖高度并存，但是对于BP如何与减肥手术结局相关的知之甚少。

方法

在这项回顾性临床队列研究中，有1034名患者完成了心理评估，并根据情绪障碍问卷对≥7的评分和中度残疾定义为筛查可能的BP阳性。还使用标准化问卷对食物成瘾（FA），阈下暴饮暴食症（BED）和非法吸毒进行了评估。

结果

与BP筛查阴性的980例（94.8％）相比，54例筛查BP阳性的患者进行减肥手术的可能性较低（5例或9.3％vs 273例，或27.9％）。可能患有BP的患者的FA患病率也明显更高（37％比13.2％），阈下BED（29.6％比8.3％）和非法药物使用（7.4％比2.1％）。

结论

在这项回顾性临床队列研究中，对BP筛查呈阳性的患者有较高的食物成瘾率，亚阈暴饮暴食症和最近非法吸毒的患病率。他们还证明了减肥手术的完成率较低。显然，还需要了解更多有关如何帮助患有躁郁症的患者应对肥胖和行为挑战的知识。