In recent years, nanoparticles have become a fashionable subject of research due to their sizes, shapes, and unique intrinsic physicochemical properties. In particular for the last 5 years, nano-Se has received tremendous attention in terms of its production, characteristic, and possible application for poultry/animal science and medical sciences. Indeed, Nano-Se is shown to be a potential source of Se for poultry/animal nutrition. However, there is an urgent need to address the questions related to nano-Se absorption, assimilation, and metabolism. It is not clear at present if major biological effects of nano-Se are due to Se-protein synthesis, direct antioxidant/prooxidant effects, or both. It is necessary to understand how metallic nano-Se can be converted into H2Se and further to SeCys to be incorporated into selenoproteins. The aforementioned issues must be resolved before nano-Se finds its way to animal/poultry production as a feed supplement and clearly this subject warrants further investigation.

中文翻译：

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深思：家禽营养与健康中的纳米硒

近年来，纳米粒子因其尺寸、形状和独特的内在物理化学性质而成为研究的热点。特别是在过去的 5 年中，纳米硒在其生产、特性以及在家禽/动物科学和医学科学中可能的应用方面受到了极大的关注。事实上，纳米硒被证明是家禽/动物营养的潜在硒来源。然而，迫切需要解决与纳米硒吸收、同化和代谢相关的问题。目前尚不清楚纳米硒的主要生物学效应是由于硒蛋白合成、直接抗氧化/促氧化作用，还是两者兼而有之。有必要了解金属纳米硒如何转化为 H2Se 和 SeCys 被整合到硒蛋白中。在纳米硒作为饲料补充剂进入动物/家禽生产之前，必须解决上述问题，显然这个问题值得进一步研究。