This article reports the first systematic literature review of system dynamics (SD) applications in health and medicine published between 1960 and 2018. We categorize SD contributions into three groups—disease‐related modeling, organizational modeling, and regional health modeling—and explore major trends and approaches. We then focus on disease‐related modeling and discuss (1) common structures underlying models of infectious and noninfectious diseases, (2) major findings and modeling insights, and (3) avenues for future modeling efforts. While application areas cover a wide range of contexts, a considerable level of quality variation is observable, particularly in regards to model documentation, use of data, and model validation. While these shortcomings are not specific to SD modeling—and other schools of modeling often suffer from similar problems—we invite the community to address the issues both as authors and reviewers. Our study provides a reference document for several exemplary SD models, which is especially useful for early career modelers.

中文翻译：

---

卫生和医学中的系统动力学建模：系统文献综述

本文报道了1960年至2018年间发表的有关卫生和医学领域中系统动力学（SD）应用的第一份系统文献综述。我们将SD贡献分为三类：与疾病相关的建模，组织建模和区域健康建模，并探讨主要趋势和方法。然后，我们将重点放在与疾病相关的建模上，并讨论（1）传染性和非传染性疾病模型的基本结构，（2）主要发现和建模见解，以及（3）未来建模工作的途径。尽管应用程序领域涵盖了广泛的上下文，但是可以观察到相当大程度的质量变化，尤其是在模型文档，数据使用和模型验证方面。尽管这些缺点不是SD建模所特有的，并且其他建模学派经常遇到类似的问题，但我们邀请社区以作者和审稿人的身份来解决这些问题。我们的研究为几种示例性SD模型提供了参考文件，这对于早期职业建模者特别有用。