The main aim of this paper is to investigate the corneal damage effects induced by mid-infrared optical parametric oscillator (OPO) radiation. Experiments were performed to determine the corneal damage thresholds of New Zealand white rabbit at the wavelength of 3743nm for exposure durations of 0.1s, 1.0s and 10.0s. Through slit-lamp biomicroscope and histopathology, corneal injury characteristics were revealed. The damage thresholds were 3.73J/cm², 7.91J/cm² and 31.1J/cm², respectively, for exposure durations of 0.1s, 1.0s and 10.0s. The damage data was correlated by an empirical equation: Radiant exposure at the threshold=9.72×exposure duration,0.46 where the units of radiant exposure and exposure duration were J/cm² and second. At near-threshold level, corneal injuries at 1 h post-exposure mainly involved the epithelium, and the epithelium damages repaired at 24-h post-exposure. There are sufficient safety margins between the damage thresholds and the maximum permitted exposures from current international laser safety standard IEC 60825-1.

中文翻译：

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3743 nm 红外光参量振荡器辐射引起的角膜损伤效应

本文的主要目的是研究中红外光参量振荡器（OPO）辐射引起的角膜损伤效应。实验确定新西兰大白兔在3743波长处的角膜损伤阈值nm 用于 0.1 的曝光持续时间小号，1.0s 和 10.0s。通过裂隙灯生物显微镜和组织病理学，揭示了角膜损伤特征。伤害阈值为 3.73焦/厘米² , 7.91J/cm ²和 31.1J/cm ²，分别用于 0.1 的曝光持续时间小号，1.0s 和 10.0s。损伤数据通过一个经验方程关联：临界点=9.72×接触期间，0.46其中辐射暴露和暴露持续时间的单位是 J/cm ²和秒。在接近阈值水平，暴露后1小时角膜损伤主要累及上皮，暴露后24小时上皮损伤得到修复。当前国际激光安全标准 IEC 60825-1 的损伤阈值和最大允许暴露之间有足够的安全裕度。