ABSTRACT

SARS-CoV-2 has resulted in a global pandemic resulting in the infections of many millions and deaths of well over a million people. The ease of SARS-CoV-2 spread and the infectious nature of the virus in humans has resulted in an urgent need for effective disinfection strategies. Ozone (O₃) is a promising disinfectant for SARS-CoV-2 due to its ability to overcome limitations with topical disinfection or sanitation products. In this work, we utilized RT-qPCR to measure RNA from a recombinant mammalian cell product, bacteriophage MS2, and SARS-CoV-2 sourced from municipal wastewater, after exposure to 4.5 and 9 ppmv O₃.

摘要

SARS-CoV-2 导致全球大流行，导致数百万人感染和超过一百万人死亡。SARS-CoV-2 易于传播以及该病毒在人类中具有传染性，因此迫切需要有效的消毒策略。臭氧 (O ₃ ) 是一种很有前途的 SARS-CoV-2 消毒剂，因为它能够克服局部消毒或卫生产品的局限性。在这项工作中，我们利用 RT-qPCR 来测量来自市政废水的重组哺乳动物细胞产物、噬菌体 MS2 和 SARS-CoV-2 的 RNA，在暴露于 4.5 和 9 ppmv O _{3 后}。