ABSTRACT Ozone disinfection has demonstrated high efficacy against enveloped and non-enveloped viruses, including viruses similar in morphology to SARS-CoV-2. Due to this efficacy, numerous gaseous and aqueous phase ozone applications have emerged to potentially inhibit virus persistence in aerosols, surfaces, and water. This review identifies the exposure requirements for virus inactivation and important safety considerations for applications within the built environment (i.e. occupied/unoccupied spaces, air/water/wastewater treatment) and healthcare settings (i.e. ozone therapy, dentistry, handwashing, treatment of personal protection equipment (PPE)). Current research needs are presented to advance the utilization of ozone as a mitigation strategy.

中文翻译：

---

与病毒灭活相关的臭氧应用的关键审查和研究需求：对 SARS-CoV-2 的潜在影响

摘要 臭氧消毒已证明对包膜和非包膜病毒具有高效能，包括形态与 SARS-CoV-2 相似的病毒。由于这种功效，已经出现了许多气态和水相臭氧应用，以潜在地抑制病毒在气溶胶、表面和水中的持久性。该审查确定了病毒灭活的暴露要求和建筑环境（即有人居住/无人居住的空间、空气/水/废水处理）和医疗保健环境（即臭氧治疗、牙科、洗手、个人防护设备处理）中应用的重要安全考虑因素(个人防护装备))。提出了当前的研究需求，以推动利用臭氧作为缓解战略。