Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health laboratory activities. Here, we announce a BioProject (PRJNA556438) dedicated to sharing complete genomes chosen to represent a range of pathogenic bacteria with regional importance to Australia and the Southwest Pacific; enriching the catalogue of globally available complete genomes for public health while providing valuable strains to regional public health microbiology laboratories. In this first step, we present 26 complete high-quality bacterial genomes. Additionally, we describe here a framework for reconstructing complete microbial genomes and highlight some of the challenges and considerations for accurate and reproducible genome reconstruction.

中文翻译：

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澳大利亚和西南太平洋地区公共卫生的完整微生物基因组


微生物病原体的完整基因组对于系统发育分析至关重要，系统发育分析日益成为核心公共卫生实验室活动的基础。在这里，我们宣布了一个生物项目 (PRJNA556438)，致力于共享被选择代表一系列对澳大利亚和西南太平洋具有区域重要性的病原菌的完整基因组；丰富全球可用的公共卫生完整基因组目录，同时为区域公共卫生微生物学实验室提供有价值的菌株。在第一步中，我们提供了 26 个完整的高质量细菌基因组。此外，我们在这里描述了重建完整微生物基因组的框架，并强调了准确和可重复的基因组重建的一些挑战和注意事项。