There is increasing evidence that calcitonin gene–related peptide (CGRP) plays a role in the development of neuropathic pain, a common feature of peripheral neuropathy. Although clinical studies have shown that anti‐CGRP monoclonal antibodies are highly efficacious for migraine headache prophylaxis, their effects on nonheadache chronic pain conditions, including neuropathic pain, in humans are unknown. Therefore, the aim of this study was to assess the effectiveness of anti‐CGRP monoclonal antibodies for neuropathic pain in patients with coexisting chronic migraine.

中文翻译：

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抗降钙素基因相关肽单克隆抗体可治疗偏头痛患者的神经性疼痛

越来越多的证据表明降钙素基因相关肽（CGRP）在神经性疼痛的发展中起着作用，神经性疼痛是周围神经病的常见特征。尽管临床研究表明抗CGRP单克隆抗体可有效预防偏头痛，但其对人类非头痛慢性疼痛状况（包括神经性疼痛）的影响尚不清楚。因此，本研究的目的是评估抗CGRP单克隆抗体对共存的慢性偏头痛患者神经性疼痛的有效性。