In ²H double quantum filtered (DQF) NMR, the various water compartments are characterized by their different residual quadrupolar interactions. The spectral separation between the different signals enables the measurement of the relaxation of each compartment and the magnetization transfer (MT) between them. In the current study, five water compartments were identified in the ²H DQF spectra of porcine spinal cord. The most prominent signal was the pair of satellites with a quadrupolar splitting of about 550 Hz. ²H DQF MRI optimized for the 550 Hz quadrupolar splitting indicated that this signal originated mainly from the white matter and it was assigned to the myelin water. This splitting does not change upon changing the orientation of the spinal cord relative to the magnetic field, indicating a liquid crystalline nature. Another site exhibiting splitting of about 1500 Hz was assigned to collagenous connective tissue. The narrow central peak was assigned to a combination of intra‐ and inter‐axonal water. The assignment of the other two sites is not certain and requires further study. The rates of MT between the various sites were recorded.

中文翻译：

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通过 2H 双量子过滤 NMR 鉴定脊髓中的水室

在² H 双量子过滤 (DQF) NMR 中，各种水隔室的特征在于它们不同的残余四极相互作用。不同信号之间的光谱分离能够测量每个隔室的弛豫以及它们之间的磁化转移 (MT)。在目前的研究中，在猪脊髓的² H DQF 光谱中鉴定了五个水室。最突出的信号是一对四极分裂的卫星，频率约为 550 Hz。²针对 550 Hz 四极分裂优化的 H DQF MRI 表明该信号主要来自白质，并分配给髓鞘水。这种分裂在改变脊髓相对于磁场的方向时不会改变，表明具有液晶性质。另一个显示约 1500 Hz 分裂的部位被指定为胶​​原结缔组织。狭窄的中心峰被指定为轴突内和轴突间水的组合。其他两个站点的分配尚不确定，需要进一步研究。记录了各个站点之间的 MT 率。