There is a need for a psychometrically-informed model identifying attitudinal and social factors explaining adherence to oral endocrine therapy (OET) for women with hormone receptor positive breast cancer. This study tested a model with variables selected by stringent psychometric criteria, including attitudes about benefit and burden, patient-practitioner alliance and confusion, and positive and negative interpersonal interactions. Self-report scales were completed by 150 current or past OET users. Fourteen correlations and six mediated pathways implied by the model were tested. All hypothesized associations were significant. This preliminary study suggests the model is a valuable framework for OET adherence research and intervention.

需要一种心理测量模型，以确定解释激素受体阳性乳腺癌女性坚持口服内分泌治疗 (OET) 的态度和社会因素。这项研究测试了一个模型，该模型具有通过严格的心理测量标准选择的变量，包括对收益和负担的态度、患者-从业者联盟和困惑，以及积极和消极的人际互动。自我报告量表由 150 名当前或过去的 OET 用户完成。测试了模型暗示的十四种相关性和六种介导途径。所有假设的关联都是显着的。这项初步研究表明，该模型是 OET 依从性研究和干预的宝贵框架。