Physical forces have a profound influence on bacterial cell physiology and disease. A striking example is the formation of catch-bonds that reinforce under mechanical stress. While mannose-binding by the Escherichia coli FimH adhesin has long been the only thoroughly studied microbial catch-bond, it has recently become clear that proteins from other species, such as staphylococci, are also engaged in such stress-dependent interactions.

中文翻译：

---

应力诱导捕获键增强细菌粘附

物理力对细菌细胞生理学和疾病有深远的影响。一个突出的例子是形成在机械应力下增强的捕捉键。虽然大肠杆菌FimH 粘附素的甘露糖结合长期以来一直是唯一经过彻底研究的微生物捕获键，但最近已经清楚的是，来自其他物种的蛋白质，如葡萄球菌，也参与了这种压力依赖性相互作用。