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The effect of tDCS applied to the dorsolateral prefrontal cortex on cycling performance and the modulation of exercise induced pain
Neuroscience Letters ( IF 2.5 ) Pub Date : 2020-12-19 , DOI: 10.1016/j.neulet.2020.135584
Megan Judge , James Hopker , Alexis R. Mauger

Transcranial direct current stimulation (tDCS) is a neuromodulatory tool purported to enhance endurance performance through reducing fatigue related perceptions, including exercise-induced pain (EIP). We examined whether tDCS of the left DLPFC (1) can reduce EIP during a fixed intensity cycling trial (FI), (2) can improve cycling time trial (TT) performance, and (3) whether this was affected by a bilateral or an extracephalic montage. This investigation was comprised of two parts (study one and two). In both studies, participants completed a 10-minute FI trial and a 15-minute TT after 10 min of 2 mA anodal left DLPFC tDCS, SHAM or no stimulation. In study one, 11 participants received tDCS via a bilateral montage. In study two, 20 participants received tDCS using an extracephalic montage. Pain was recorded throughout the FI and TT trials, with power output (PO) monitored during the TT. Study one saw no significant changes in pain (tDCS 4.3 ± 2.0; SHAM 4.0 ± 1.8; control 3.8 ± 1.4) during the FI trial and no significant differences in distance covered, pain or PO in the TT. In study two there were no differences in pain reported in the FI trial, or distance covered (P = 0.239), pain or PO in the TT. In summary, tDCS of the DLPFC did not induce analgesia and provided no ergogenic effect for TT performance, moreover these observations were consistent across both the extracephalic and bilateral montage. These findings are in line with an increasing number of studies demonstrating the inconsistent effects of tDCS.



中文翻译:

tDCS应用于背外侧前额叶皮层对骑自行车表现和运动诱发疼痛的调节作用

经颅直流电刺激(tDCS)是一种神经调节工具,旨在通过减少疲劳相关的知觉(包括运动诱发的疼痛(EIP))来增强耐力表现。我们检查了左DLPFC的tDCS(1)是否可以在固定强度的自行车试验(FI)期间降低EIP,(2)可以改善自行车时间试验(TT)的性能,以及(3)这是否受双侧或双侧影响。脑外蒙太奇。这项调查包括两个部分(研究一和研究二)。在两项研究中,参与者在10分钟的2 mA阳极左DLPFC tDCS,SHAM或无刺激后10分钟完成了10分钟的FI试验和15分钟的TT。在研究一中,有11名参与者通过双边蒙太奇收到了tDCS。在研究二中,有20名参与者使用脑外蒙太奇接收了tDCS。在FI和TT试验中记录了疼痛,在TT期间监控功率输出(PO)。研究一项发现,FI试验期间疼痛无明显变化(tDCS 4.3±2.0; SHAM 4.0±1.8;对照3.8±1.4),TT的距离,疼痛或PO均无显着差异。在研究二中,FI试验中报告的疼痛或所覆盖的距离没有差异(P = 0.239),TT中的疼痛或PO。总之,DLPFC的tDCS不会引起镇痛作用,也不会对TT性能产生人为作用,而且这些观察结果在脑外和双侧蒙太奇中均一致。这些发现与越来越多的研究表明tDCS的影响不一致。

更新日期:2020-12-25
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