Abstract

An enhanced swift indirect method for the determination of both free and bound 3-monochloropropane-1,2-diol has been established. The advantages include reduced sample preparation time (1 h instead of several hours), rapid triple quadrupole gas chromatography−mass spectrometry detection (12 min rather than 30 min in average) combined with amplified selectivity and sensitivity. The enhanced method has been entirely validated. The limits of quatification and detection were estimated and were found to be less than 2 and 0.5 µg/kg, respectively. The recoveries at different spiked levels ranged from 98 to 106%. The reproducibility (expressed as relative standard deviation) was less than 8% while measurement uncertainty was in the range of ±18%.

中文翻译：

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气相色谱-串联质谱法测定食品中结合的和游离的3-氯丙烷-1,2-二元醇的增强快速分析方法的验证

摘要

建立了一种增强的快速间接测定游离和结合的3-一氯丙烷-1,2-二醇的方法。优点包括减少样品制备时间（从1小时而不是数小时），快速的三重四极杆气相色谱-质谱检测（平均12分钟而不是30分钟），并具有增强的选择性和灵敏度。增强方法已被完全验证。估计了量化和检出限，分别低于2和0.5 µg / kg。不同加标水平下的回收率在98％至106％之间。再现性（表示为相对标准偏差）小于8％，而测量不确定度在±18％范围内。