Fast acquisition of a first computed tomography (CT) scan after traumatic brain injury (TBI) is recommended. This study is aimed at investigating whether the length of the period preceding initial CT scan influences mortality in patients with leading TBI. A retrospective cohort analysis of patients registered in the TraumaRegister DGU® was conducted including adult patients with TBI, defined as Abbreviated Injury Scale_Head ≥ 3 and GCS ≤ 13 who had been treated in level 1 or 2 trauma centers from 2007–2016. Patients were grouped according to time intervals either from trauma or from admission to CT. A total of 6904 patients met the inclusion criteria. Mean time period from trauma to hospital admission was 68.8 min. From admission to first CT, a mean of 19.0 min elapsed. Trauma severity was higher in groups with a longer duration from trauma to CT as represented by a mean (± standard deviation) Injury Severity Score (ISS) of 19.8 ± 9.0, 20.7 ± 9.3, and 21.4 ± 7.5 and similar distribution of mortality of 24.9%, 29.9%, and 36.3% in the ≤ 60-min, 61–120-min, and ≥ 121-min groups, respectively. An adjusted multivariable logistic regression model showed a significant influence of the level of the trauma center (p = 0.037) but not for interval from admission to CT (p = 0.528). TBI patients with a longer time span from trauma to first CT were more severely injured and demonstrated a worse prognosis, but received a CT scan faster when duration from admission is observed. The duration until the CT scan was obtained showed no significant impact on the mortality.

建议在创伤性脑损伤 (TBI) 后快速获取第一次计算机断层扫描 (CT) 扫描。本研究旨在调查初始 CT 扫描前的时间长短是否影响先导性 TBI 患者的死亡率。对 TraumaRegister DGU® 注册的患者进行了回顾性队列分析，包括成年 TBI 患者，定义为缩写伤害量表_头≥ 3 且 GCS ≤ 13，并于 2007-2016 年在 1 级或 2 级创伤中心接受治疗。患者根据从创伤或入院到 CT 的时间间隔进行分组。共有6904名患者符合纳入标准。从外伤到入院的平均时间为 68.8 分钟。从入院到第一次 CT，平均时间为 19.0 分钟。从创伤到 CT 持续时间较长的组的创伤严重程度更高，平均（± 标准差）损伤严重程度评分 (ISS) 为 19.8 ± 9.0、20.7 ± 9.3 和 21.4 ± 7.5，死亡率分布相似，为 24.9在≤ 60 分钟、61–120 分钟和≥ 121 分钟组中分别为 %、29.9% 和 36.3%。调整后的多变量逻辑回归模型显示创伤中心的水平有显着影响（p= 0.037) 但不适用于从入院到 CT 的时间间隔 ( p = 0.528)。从外伤到第一次 CT 时间跨度较长的 TBI 患者受伤更严重，预后更差，但在观察到入院时间后，接受 CT 扫描的速度更快。获得 CT 扫描的持续时间显示对死亡率没有显着影响。