The heart and the liver display multifaceted, complex interactions that can be divided into cardiac effects of liver disease, hepatic effects of heart disease, and disease processes affecting both organs. In part 1 of this 2 part series, we discuss how acute and chronic heart failure can have devastating effects on the liver, such as acute cardiogenic liver injury and congestive hepatopathy. On the other hand, primary liver disease, such as cirrhosis, can lead to a plethora of cardiac insults representative in cirrhotic cardiomyopathy as systolic dysfunction, diastolic dysfunction, and electrophysiological disturbances. Nonalcoholic fatty liver disease has long been associated with cardiovascular events that increase mortality. The management of both disease processes changes when the other organ system becomes involved. This consideration is important with regard to a variety of interventions, most notably transplantation of either organ, as risk of complications dramatically rises in the setting of both heart and liver disease (discussed in part 2). As our understanding of the intricate communication between the heart and liver continues to expand so does our management.

心脏和肝脏表现出多方面、复杂的相互作用，可分为肝病对心脏的影响、心脏病对肝的影响以及影响两个器官的疾病过程。在这个由两部分组成的系列的第一部分中，我们讨论急性和慢性心力衰竭如何对肝脏产生破坏性影响，例如急性心源性肝损伤和充血性肝病。另一方面，原发性肝病，例如肝硬化，可导致过多的心脏损伤，以肝硬化心肌病为代表，如收缩功能障碍、舒张功能障碍和电生理障碍。非酒精性脂肪肝长期以来一直与增加死亡率的心血管事件有关。当其他器官系统参与时，这两种疾病过程的管理都会发生变化。这种考虑对于各种干预措施都很重要，尤其是任一器官移植，因为在心脏病和肝脏疾病的情况下，并发症的风险急剧上升（在第 2 部分中讨论）。随着我们对心脏和肝脏之间复杂沟通的理解不断加深，我们的管理也在不断加深。