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Review on Synthesis of Bio-active Coumarin-fused Heterocyclic Molecules
Current Organic Chemistry ( IF 1.7 ) Pub Date : 2020-10-31 , DOI: 10.2174/1385272824999200709125717
Geetika Patel 1 , Subhash Banerjee 1
Affiliation  

The literature survey reveals that the individual coumarin and heterocyclic molecules have biological and pharmaceutical activities. Moreover, integrated coumarinfused heterocyclic compounds have shown interesting biological and physiochemical properties and thus, designing and development of coumarin-fused heterocyclic molecules are of great interest in the field of synthetic organic chemistry. Several coumarin-fused heterocyclic molecules have been synthesized by using different strategies such as multistep method, one-pot multi-component protocol, coupling and condensation method. The wide applications of integrated coumarin-fused heterocyclic molecules stimulated interest among researchers to develop different methodologies for the synthesis of novel fused molecules. As a consequence, several research articles, papers and review articles have been published in the literature. In this review article, we have presented various methods for the synthesis of different class of coumarin-fused heterocyclic molecules and their applications in chemical, optical, pharmaceutical and other useful applications.



中文翻译:

具有生物活性的香豆素稠合杂环分子的合成研究进展

文献调查显示,香豆素和杂环分子具有生物学和药学活性。而且,整合的香豆素稠合的杂环化合物已经显示出令人感兴趣的生物学和物理化学性质,因此,香豆素稠合的杂环分子的设计和开发在合成有机化学领域中具有极大的兴趣。通过使用不同的策略,例如多步法,一锅多组分方案,偶联和缩合法,已经合成了几种香豆素稠合的杂环分子。集成香豆素融合的杂环分子的广泛应用激发了研究人员的兴趣,以开发出用于合成新型融合分子的不同方法。结果,几篇研究文章 文献和评论文章已在文献中发表。在这篇综述文章中,我们介绍了用于合成不同种类香豆素稠合杂环分子的各种方法及其在化学,光学,制药和其他有用应用中的应用。

更新日期:2020-12-18
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