Objective:To review the effects of whole body vibration for patients with Parkinson’s disease.Design:Randomized clinical trials comparing whole body vibration with no vibration or conventional physical therapy for patients with Parkinson’s disease were searched up to July 31, 2019.Results:Seven studies with 196 patients were included for quantitative analysis. No significant difference was found between groups in motor score of unified Parkinson’s disease rating scale (UPDRS-III) (WMD [weighted mean difference] = −1.75, 95% CI, −5.40 to 1.90, I2 = 45.8%), functional reach test (SMD [standardized mean difference] = 0.21, 95% CI, −0.29 to 0.71; I2 = 0%), and other balance tests (including Berg balance test and Tinetti score) (SMD = 0.39, 95% CI, −0.01 to 0.80; I2 = 0%). No statistical difference was detected in walking velocity as well (WMD = −0.05, 95% CI, −0.17 to 0.06; I2 = 0%). In contrast, the pooled analysis from four studies on the Time Up and Go test showed favorable results for whole body vibration (WMD = −1.59, 95% CI, −2.90 to −0.28, I2 = 0%).Conclusion:Whole body vibration may not be beneficial over placebo or conventional physical therapy in overall motor function, balance, and walking velocity in patients with Parkinson’s disease. However, it might have positive effects on sit to stand transitions or turning.

中文翻译：

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全身振动对帕金森病患者运动功能的影响：系统评价和荟萃分析

目的：回顾全身振动对帕金森病患者的影响。设计：检索截至 2019 年 7 月 31 日，比较全身振动与不振动或常规物理治疗对帕金森病患者的随机临床试验。结果：七项研究纳入 196 名患者进行定量分析。帕金森病统一评分量表 (UPDRS-III) 的运动评分组间无显着差异 (WMD [加权平均差] = -1.75, 95% CI, -5.40 至 1.90, I2= 45.8%），功能范围测试（SMD [标准化平均差] = 0.21, 95% CI，-0.29 至 0.71；I2= 0%）和其他平衡测试（包括 Berg 平衡测试和 Tinetti 评分）（SMD = 0.39，95% CI，-0.01 至 0.80；I2= 0%）。步行速度也未检测到统计学差异（WMD = -0.05, 95% CI, -0.17 至 0.06；I2= 0%）。相比之下，关于 Time Up and Go 测试的四项研究的汇总分析显示全身振动的良好结果（WMD = -1.59, 95% CI, -2.90 到 -0.28, I2= 0%)。结论：全身振动在帕金森病患者的整体运动功能、平衡和步行速度方面可能不优于安慰剂或常规物理治疗。但是，它可能对坐立转换或转身产生积极影响。