Abstract

Highly functionalized piperidines are a versatile class of nitrogen-containing heterocycles which find broad applications in numerous fields such as medicinal chemistry and drug discovery research. The synthesis of this privileged scaffold from readily available materials remains is a hot topic research for the synthetic chemistry community. This review aims to describe the different strategies developed so far for the synthesis of highly functionalized piperidines.

中文翻译：

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高官能度哌啶的多组分合成

抽象的

高度官能化的哌啶是一类通用的含氮杂环，在诸如药物化学和药物发现研究等许多领域中都有广泛的应用。由现成的材料合成这种特有的支架仍然是合成化学界的热门研究。这篇综述旨在描述迄今为止为合成高度官能化的哌啶而开发的不同策略。