Abstract Bone quality is a combination of the material and structural properties of bone. Reductions in bone quality parameters, such as the degree of collagen fiber orientation, mineralization, mineral maturity, and crystallinity, affect bone strength. However, the relationships among the bone quality parameters remain poorly understood. In this work, we investigated the relationships among collagen fiber orientation and other bone quality parameters in the rat femur using Fourier transform infrared spectroscopic imaging and infrared dichroism imaging. In cortical bone, collagen fibers were found to be aligned longitudinally and an increase in the degree of mineral maturity or mineralization was associated with an increase in the degree of collagen fiber orientation.

中文翻译：

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胶原纤维取向、矿化、矿物成熟度和结晶度之间的关系

摘要 骨质量是骨的材料和结构特性的综合。骨质量参数的降低，例如胶原纤维取向、矿化、矿物质成熟度和结晶度的程度，会影响骨强度。然而，骨质量参数之间的关系仍然知之甚少。在这项工作中，我们使用傅里叶变换红外光谱成像和红外二色性成像研究了大鼠股骨中胶原纤维取向与其他骨质量参数之间的关系。在皮质骨中，发现胶原纤维纵向排列，矿物质成熟度或矿化程度的增加与胶原纤维取向程度的增加有关。