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Two new 2-phenylethylchromones from artificial agarwood by holing method
Journal of Asian Natural Products Research ( IF 1.7 ) Pub Date : 2020-12-18 , DOI: 10.1080/10286020.2020.1860029
Pan Xiang 1 , Yan-Bo Zeng 1 , Hao Wang 1 , Fan-Dong Kong 1 , Hui-Qin Chen 1 , Wen-Li Mei 1 , Hao-Fu Dai 1
Affiliation  

Abstract

Two new 2-(2-phenylethyl)chromone derivatives (12) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by extensive spectroscopic analyses, including UV, IR, one- and two-dimensional NMR and HRESIMS measurements. Bioassay tests of these two new compounds showed compounds 1 and 2 had weak inhibitory activity against acetylcholinesterase at a concentration of 50.0 μg/ml.



中文翻译:

人工沉香中两种新的2-苯乙基色酮打孔法

摘要

沉香( Aquilaria sinensis (Lour.) Gilg) 孔法诱导的人工沉香乙酸乙酯提取物中分离出两种新的2-(2-苯乙基)色酮衍生物( 12 ) ,并首次从该属中分离得到。时间。这两种新化合物的结构通过广泛的光谱分析得到阐明,包括 UV、IR、一维和二维 NMR 和 HRESIMS 测量。这两种新化合物的生物测定试验表明,化合物12在 50.0 μg/ml 浓度时对乙酰胆碱酯酶具有弱抑制活性。

更新日期:2020-12-18
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