Abstract The effect of xylitol tablets with (XPT) and without (XT) red propolis on salivary parameters, dental biofilm and acceptability of adolescents was evaluated through a blinded randomized crossover clinical trial. Healthy volunteers were allocated in the XPT and XT groups with a 30-day washout period for consumption of two tablets/dayfor seven days. An increase in salivary parameters was only observed immediately after tablet consumption, without differences between XPT and XT. The results for total microorganisms were similar, but XT was better in controlling Streptococcus spp. Rothia dentocariosa and Streptococcus salivarius were the most frequent in the biofilm and saliva, respectively. XPT and XT showed similar acceptability, with the highest purchase intention for XT. Although propolis did not enhance the properties of XT, further studies testing different protocols and follow-up are necessary; XT controlled Streptococcus spp. in biofilms, which demonstrate its potential for clinical application.

中文翻译：

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含和不含红蜂胶的木糖醇片对青少年唾液参数、牙齿生物膜和感官可接受性的影响：一项随机交叉临床试验

摘要 通过盲法随机交叉临床试验评估了含 (XPT) 和不含 (XT) 红蜂胶的木糖醇片对青少年唾液参数、牙齿生物膜和可接受性的影响。健康志愿者被分配到 XPT 和 XT 组，有 30 天的清除期，每天服用两片，共 7 天。仅在服用片剂后立即观察到唾液参数的增加，XPT 和 XT 之间没有差异。总微生物的结果相似，但 XT 在控制链球菌方面更好。Rothia dentocariosa 和 Streptococcus salivarius 分别在生物膜和唾液中最常见。XPT 和 XT 表现出相似的可接受性，对 XT 的购买意愿最高。虽然蜂胶没有增强XT的特性，需要进一步研究测试不同的方案和后续行动；XT 控制的链球菌属。在生物膜中，这证明了其临床应用的潜力。