Cancer is a heterogeneous disease which can influence many facets of the human physiology. Treatments and therapies of cancer are as diverse as the illness itself and often come with toxic side effects. In many reviews, researchers regularly summarize the newest results and try to untangle the complexity of cancer and cancer‐related research.¹ This review aims to connect recent research on the field of molecular biology of cancer with recent results from exercise physiology that were published in Acta Physiologica.

A sedentary lifestyle as it is led by modern society nowadays is a leading cause of diseases and disabilities.² Physical activity and exercise are described as a potential prevention against a diversity of chronic conditions, including cancer.³ Exercise training was brought into focus lately as a toxin‐free addition to promote a positive outcome of cancer treatments (surgery, chemo‐, radiation‐, hormonal therapy). Even Drosophila melanogaster was recruited as a new model for exercise research in order to enable large scale studies with broad sets of parameters.⁴ Physical exercise can counteract many cancer promoting factors, such as high inflammatory levels, high levels of adipose tissue, cachexia, cardiovascular diseases⁵ and a low mitochondrial capacity. Therefore, researchers are more and more eager to understand the molecular mechanisms that promote the manifold of effects that exercise can have on our physiology.^6-9

癌症是一种异质性疾病，可以影响人类生理学的许多方面。癌症的治疗方法和治疗方法与疾病本身一样多种多样，并且常常伴有毒副作用。在许多评论中，研究人员定期总结最新结果，并试图理清癌症和癌症相关研究的复杂性。 ¹本综述旨在将癌症分子生物学领域的最新研究与发表在 Acta Physiologica 上的运动生理学最新结果联系起来。

现代社会久坐的生活方式是导致疾病和残疾的主要原因。 ²体力活动和锻炼被描述为预防多种慢性病（包括癌症）的潜在方法。 ³运动训练作为一种无毒补充手段，可促进癌症治疗（手术、化疗、放疗、激素治疗）取得积极成果，最近受到关注。甚至黑腹果蝇也被招募作为运动研究的新模型，以便能够进行具有广泛参数集的大规模研究。 ⁴体育锻炼可以抵消许多促癌因素，例如高炎症水平、高水平脂肪组织、恶病质、心血管疾病⁵和线粒体容量低。因此，研究人员越来越渴望了解运动对我们生理机能产生多种影响的分子机制。 ^6-9