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Dysphagia in neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody disease as a surrogate of brain involvement?
European Journal of Neurology ( IF 4.5 ) Pub Date : 2020-12-18 , DOI: 10.1111/ene.14691
Marc Pawlitzki 1 , Sigrid Ahring 1 , Leoni Rolfes 1 , Rainer Dziewas 1 , Tobias Warnecke 1 , Sonja Suntrup-Krueger 1, 2 , Heinz Wiendl 1 , Luisa Klotz 1 , Sven G Meuth 1 , Bendix Labeit 1, 2
Affiliation  

Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are demyelinating disorders that typically affect the optic nerves and the spinal cord. However, recent studies have demonstrated various forms of brain involvement indicating encephalitic syndromes, which consequently are included in the diagnostic criteria for both. Swallowing is processed in a distributed brain network and is therefore disturbed in many neurological diseases. The aim of this study was to investigate the occurrence of oropharyngeal dysphagia in NMOSD and MOGAD using flexible endoscopic evaluation of swallowing (FEES) as a surrogate parameter of brain involvement.

中文翻译:

视神经脊髓炎谱系障碍和髓鞘少突胶质细胞糖蛋白抗体疾病中的吞咽困难作为大脑受累的替代物?

视神经脊髓炎谱系障碍 (NMOSD) 和髓鞘少突胶质细胞糖蛋白抗体病 (MOGAD) 是脱髓鞘疾病,通常会影响视神经和脊髓。然而,最近的研究表明,各种形式的大脑受累表明脑炎综合征,因此这两种情况都包含在诊断标准中。吞咽在分布式脑网络中进行处理,因此在许多神经系统疾病中受到干扰。本研究的目的是使用灵活的吞咽内窥镜评估 (FEES) 作为大脑受累的替代参数,研究 NMOSD 和 MOGAD 中口咽吞咽困难的发生情况。
更新日期:2020-12-18
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