Four novel 3,5-bifluorobenzenetelluronic triorganotin(IV) esters, namely (3,5-F₂C₆H₃TeOH)₂(μ-O)₂(OSnR₃)₄ (R = Me: 1, R = Ph: 2) and (3,5-F₂C₆H₃TeOH)(OSnR₃)₄ (R = Me: 3, R = Ph: 4) have been synthesized and characterized by the reaction of deprotonated 3,5-bifluorobenzenetelluronic acid ligand and corresponding R₃SnCl (R = Me, Ph). All the complexes have been characterized by means of elemental analysis, FT-IR, NMR (¹H, ¹³C, ¹¹⁹Sn) spectroscopy, and X-ray crystallography. Structural analyses of these complexes reveal that complexes 1 and 2 exhibit centrosymmetric dimeric structure with an almost planar four-membered Te₂(μ₂-O)₂ core in the center, while 3 and 4 form monomeric structure with a single Te center. The Te atoms adopt octahedral geometry in all the complexes. Complexes 1–4 could form 2D or 3D supramolecular structures through intermolecular C-H···F or C-H···O interactions. Preliminary in vitro cytostatic studies show that complexes 1–4 exhibit effective cytostatic activity against human cervix adenocarcinoma cell lines (HeLa) and human hepatocellular carcinoma cell lines (HepG-2). For further assessing apoptosis properties of complex 2, the levels of apoptosis were examined. The BSA-binding properties were investigated by means of fluorescence titration. The results indicate that complexes 1–4 could quench the intrinsic fluorescence of BSA.

四种新颖的3,5-二氟苯碲脲三有机锡（IV）酯，即（3,5-F ₂ C ₆ H ₃ TeOH）₂（μ-O）₂（OSnR ₃）₄（R = Me：1，R = Ph：合成了2）和（3,5-F ₂ C ₆ H ₃ TeOH）（OSnR ₃）₄（R = Me：3，R = Ph：4）并通过去质子化的3,5-二氟苯碲酸反应来表征配体和相应的R ₃SnCl（R ＝ Me，Ph）。所有的配合物已通过元素分析，FT-IR，NMR（¹ H，¹³ C，¹¹⁹ Sn）光谱和X射线晶体学进行了表征。这些复合物的结构分析表明，复合物1和2显示出中心对称二聚体结构具有几乎平面的四元碲₂（μ ₂ -O）₂芯在中心，而3和4与单个碲中心形式的单体结构。Te原子在所有配合物中均采用八面体几何形状。复杂1 – 4可以通过分子间CH··F或CH··O相互作用形成2D或3D超分子结构。初步体外抑制细胞生长的研究表明，配合物1 - 4对人宫颈腺癌细胞系（HeLa细胞）和人肝癌细胞系（人肝癌HepG-2）显示出有效的抑制细胞生长的活性。为了进一步评估复合物2的凋亡特性，检查了凋亡水平。通过荧光滴定法研究了BSA的结合特性。结果表明，复合物1 - 4也打消BSA的内源荧光。