Abstract

Personal values are thought to modulate value-based decisions, but the neural mechanisms underlying this influence remain unclear. Using a Lottery Choice Task functional brain imaging experiment, we examined the associations between personal value for hedonism and security (based on the Schwartz Value Survey) and subjective neurocognitive processing of reward and loss probability and magnitude objectively coded in stimuli. Hedonistic individuals accepted more losing stakes and showed increased right dorsolateral prefrontal and striatal and left parietal responses with increasing probability of losing. Individuals prioritizing security rejected more stakes and showed reduced right inferior frontal and amygdala responses with increasing stake magnitude, but increased precuneus responses for high-magnitude high-winning probability. With higher hedonism, task-related functional connectivity with the whole brain was higher in right insula and lower in bilateral habenula. For those with higher security ratings, whole-brain functional connectivity was higher in bilateral insula, supplementary motor areas, right superior frontal gyrus, dorsal anterior cingulate cortex, and lower in right middle occipital gyrus. These findings highlight distinct neural engagement across brain systems involved in reward and affective processing, and cognitive control that subserves how individual differences in personal value for gaining rewards or maintaining status quo modulate value-based decisions

中文翻译：

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神经反应揭示了个人价值观和基于价值的决策之间的关联

摘要

人们认为个人价值观会调节基于价值的决策，但这种影响背后的神经机制仍不清楚。使用彩票选择任务功能性脑成像实验，我们检查了享乐主义和安全性的个人价值（基于施瓦茨价值调查）与在刺激中客观编码的奖励和损失概率和幅度的主观神经认知处理之间的关联。享乐主义的个体接受更多的失败风险，并表现出右背外侧前额叶、纹状体和左顶叶反应增加，失败的可能性增加。优先考虑安全的个人拒绝更多的赌注，并且随着赌注幅度的增加，右下额叶和杏仁核的反应减少，但对高幅度高获胜概率的楔前叶反应增加。享乐主义越高，与整个大脑的任务相关功能连接在右脑岛越高，在双侧缰骨越低。对于安全等级较高的人，双侧脑岛、辅助运动区、右侧额上回、背侧前扣带回皮质和右侧枕中回较低的全脑功能连接性较高。这些发现突出了涉及奖励和情感处理的大脑系统中不同的神经参与，以及促进个人价值的个体差异如何获得奖励或维持的认知控制 辅助运动区、右侧额上回、背侧前扣带回皮质和右侧枕中回下部。这些发现突出了涉及奖励和情感处理的大脑系统中不同的神经参与，以及促进个人价值的个体差异如何获得奖励或维持的认知控制 辅助运动区、右侧额上回、背侧前扣带回皮质和右侧枕中回下部。这些发现突出了涉及奖励和情感处理的大脑系统中不同的神经参与，以及促进个人价值的个体差异如何获得奖励或维持的认知控制现状调节基于价值的决策