ABSTRACT

The aim of this review was to estimate the prevalence of cardiometabolic disease indicators in people with psychotic disorders in secure settings. A PRISMA guided systematic search and appraisal was conducted for studies of metabolic disease indicators in samples of adult male and female inpatients in secure psychiatric hospitals and inmates in custodial centres with diagnoses of psychotic disorders. Seventeen studies were selected for review. An ability to validly summarise and compare prevalence data across studies were limited by the extent of methodological heterogeneity. The weighted pooled prevalence rates were determined to be: metabolic syndrome 23.5% (N = 1,390, 95% CI 21.3, 25.7), diabetes 11.2% (N = 2,582, 95% CI 9.9, 12.4), dyslipidaemia 29.2% (N = 1,135, 95% CI 26.6, 31.9), hypertension 25.0% (N = 857, 95% CI 22.1, 27.9), being overweight or obese 72.4% (N = 840, 95% CI 69.4, 75.5) and cardiovascular disease 15.6% (N = 1,047, 95% CI 13.4, 17.8). The prevalence of CMD indicators in people with psychotic disorders in secure settings were predominantly higher compared to the general population and either similar or lower compared to people with psychotic disorders in the community.

摘要

这篇综述的目的是评估安全环境下精神病患者的心脏代谢疾病指标的流行程度。进行了PRISMA指导的系统搜索和评估，以研究安全的精神病医院的成年男性和女性住院病人以及诊断为精神病的羁押中心的囚犯样本中的代谢疾病指标。选择了十七项研究进行审查。有效地汇总和比较研究中患病率数据的能力受到方法学异质性程度的限制。加权合并患病率确定为：代谢综合征23.5％（N = 1,390，95％CI 21.3，25.7），糖尿病11.2％（N = 2,582，95％CI 9.9，12.4），血脂异常29.2％（N = 1,135） ，95％CI 26.6、31.9），高血压25.0％（N = 857、95％CI 22.1、27.9），超重或肥胖者为72.4％（N = 840，95％CI 69.4，75.5）和心血管疾病为15.6％（N = 1,047，95％CI 13.4，17.8）。在安全场所中，精神病患者的CMD指标普遍高于一般人群，而社区中精神病患者的CMD指标则相近或较低。