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ZFHX3 knockdown dysregulates mitochondrial adaptations to tachypacing in atrial myocytes through enhanced oxidative stress and calcium overload
Acta Physiologica ( IF 5.6 ) Pub Date : 2020-12-17 , DOI: 10.1111/apha.13604
Baigalmaa Lkhagva, Yung‐Kuo Lin, Yao‐Chang Chen, Wan‐Li Cheng, Satoshi Higa, Yu‐Hsun Kao, Yi‐Jen Chen

To investigate the role of zinc finger homeobox 3 gene (ZFHX3) in tachypacing‐induced mitochondrial dysfunction and explore its molecular mechanisms and potential as a therapeutic target in atrial fibrillation (AF).

中文翻译:

ZFHX3 敲低通过增强的氧化应激和钙超载使线粒体对心房肌细胞过速的适应失调

研究锌指同源框 3 基因 ( ZFHX3 ) 在心动过速诱导的线粒体功能障碍中的作用,并探讨其分子机制和作为心房颤动 (AF) 治疗靶点的潜力。
更新日期:2020-12-17
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