ABSTRACT The aim of this study was to evaluate the influence of alpha-tricalcium phosphate (α-TCP) in the physical-chemical properties of an experimental adhesive resin and to analyze the immediate and long-term properties of caries-affected dentin (CAD) after selective removal to soft dentin restored with or without the α-TCP group. An experimental adhesive resin was formulated with BisGMA, HEMA (66.66:33.33 wt.%), and a photoinitiator system. α-TCP was added at 2 wt.% into this base resin, and one group remained without α-TCP as control. The adhesives were analyzed for softening in solvent, polymerization kinetics, and degree of conversion (DC). Human teeth naturally affected by caries were submitted to selective removal of carious dentin and were restored with the experimental adhesives. The teeth were evaluated by immediate and long-term (storage in simulated body fluid) tests: microtensile bond strength (μ-TBS), Knoop hardness of dentin, and mineral deposition by micro-Raman spectroscopy. The experimental adhesive resin with α-TCP showed higher initial Knoop hardness than the control group (p 0.05) and the DC (p>0.05). The polymerization rate of α-TCP group was higher than the control. There was no difference for μ-TBS between groups (p>0.05). The hardness of CAD increased in 100 and 200 μm from the adhesive interface after three months (p

中文翻译：

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添加α-磷酸三钙的粘合剂系统，用于在受龋齿影响的牙本质上沉积矿物质

摘要 本研究的目的是评估 α-磷酸三钙 (α-TCP) 对实验性粘合剂树脂物理化学性质的影响，并分析龋齿影响牙本质 (CAD) 的近期和长期性质。在有或没有 α-TCP 组的情况下，选择性去除软牙本质后恢复。实验性粘合剂树脂由 BisGMA、HEMA (66.66:33.33 wt.%) 和光引发剂系统配制而成。将 2 wt.% 的α-TCP 添加到该基础树脂中，剩下的一组没有α-TCP 作为对照。分析粘合剂在溶剂中的软化、聚合动力学和转化度 (DC)。自然受龋齿影响的人类牙齿接受选择性去除龋齿牙本质，并用实验粘合剂修复。牙齿通过即时和长期（储存在模拟体液中）测试进行评估：微拉伸粘合强度 (μ-TBS)、牙本质的努氏硬度和显微拉曼光谱的矿物质沉积。具有 α-TCP 的实验粘合剂树脂显示出比对照组 (p = 0.05) 和 DC (p>0.05) 更高的初始努普硬度。α-TCP 基团的聚合速率高于对照。μ-TBS 组间没有差异（p>0.05）。三个月后，CAD 的硬度从粘合界面增加 100 和 200 μm（p α-TCP 基团的聚合速率高于对照。μ-TBS 组间没有差异（p>0.05）。三个月后，CAD 的硬度从粘合界面增加 100 和 200 μm（p α-TCP 基团的聚合速率高于对照。μ-TBS 组间没有差异（p>0.05）。三个月后，CAD 的硬度从粘合界面增加 100 和 200 μm（p