Abstract

Two new cytochalasins, deacetyl-19-epi-cytochalasin P1 (1), deacetyl-19,20-epoxycytochalasin D (2) were isolated from the endophytic fungus Diaporthe sp. RJ-47, along with four known compounds deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C (3), 19,20-epoxycytochalasin Q (4), 19,20-epoxycytochalasin C (5) and deacetyl-19,20-epoxy cytochalasin C (6). Their structures were unambiguously elucidated on the basis of the comprehensive analysis of extensive spectroscopic data. The antimicrobial effects of these compounds were evaluated.

中文翻译：

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六个来自内生Diaporthe sp。的19,20-环氧细胞松弛素。RJ-47

摘要

从内生真菌Diaporthe sp。中分离出两个新的细胞松弛素，脱乙酰19-上皮细胞松弛素P1（1），脱乙酰19,20-环氧细胞松弛素D（2）。RJ-47，以及四种已知化合物deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C（3），19,20-epoxycytochalasin Q（4），19,20-epoxycytochalasin C（5）和脱乙酰基19,20-环氧细胞松弛素C（6）。在广泛的光谱数据的综合分析的基础上，明确阐明了它们的结构。评价了这些化合物的抗微生物作用。