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Six 19,20-epoxycytochalasans from endophytic Diaporthe sp. RJ-47
Natural Product Research ( IF 1.9 ) Pub Date : 2020-12-16
Qiong Zhang, Zhi-pu Huang, Yu-ying Zhao, Qing Zhao, Jian-hong Chen, Wei-guang Ma, Xiao-mei Zhang

Abstract

Two new cytochalasins, deacetyl-19-epi-cytochalasin P1 (1), deacetyl-19,20-epoxycytochalasin D (2) were isolated from the endophytic fungus Diaporthe sp. RJ-47, along with four known compounds deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C (3), 19,20-epoxycytochalasin Q (4), 19,20-epoxycytochalasin C (5) and deacetyl-19,20-epoxy cytochalasin C (6). Their structures were unambiguously elucidated on the basis of the comprehensive analysis of extensive spectroscopic data. The antimicrobial effects of these compounds were evaluated.



中文翻译:

六个来自内生Diaporthe sp。的19,20-环氧细胞松弛素。RJ-47

摘要

从内生真菌Diaporthe sp。中分离出两个新的细胞松弛素,脱乙酰19-上皮细胞松弛素P1(1),脱乙酰19,20-环氧细胞松弛素D(2)。RJ-47,以及四种已知化合物deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C(3),19,20-epoxycytochalasin Q(4),19,20-epoxycytochalasin C(5)和脱乙酰基19,20-环氧细胞松弛素C(6)。在广泛的光谱数据的综合分析的基础上,明确阐明了它们的结构。评价了这些化合物的抗微生物作用。

更新日期:2020-12-16
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