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Clinical Risk Factors for Therapeutic Lithium-Associated Electrocardiographic Changes in Patients With Bipolar Disorder.
Journal of Clinical Psychopharmacology ( IF 2.9 ) Pub Date : 2019-12-14 , DOI: 10.1097/jcp.0000000000001164
Pao-Huan Chen , Yu-Hsun Kao , Chi-Kang Chang 1 , Yen-Kuang Lin 2 , Yuan-Feng Lin , Yi-Jen Chen
Affiliation  

Lithium, a common medication used in bipolar disorder treatment, can exert an inhibitory effect on sodium and potassium channels and potentially cause cardiac electrical conduction disturbance and corrected QT (QTc) prolongation. This study aimed to examine whether lithium at therapeutic levels can change electrocardiographic parameters in different groups of patients with bipolar disorder and to identify the potential clinical risk factors.

中文翻译:

双相情感障碍患者治疗性锂相关心电图变化的临床危险因素。

锂是双相情感障碍治疗中常用的药物,可对钠和钾通道产生抑制作用,并可能导致心脏电传导障碍和纠正 QT (QTc) 延长。本研究旨在检查治疗水平的锂是否可以改变不同双相情感障碍患者组的心电图参数,并确定潜在的临床危险因素。
更新日期:2020-12-17
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