Background

Visualizing educational contents makes learning more efficient and effective especially in the area such as molecular toxicology, which is time consuming and intellectually taxing to learn.

Objective

A design principle based on cognitive neuroscience was developed for spatiotemporality of information and optimized virtual reality (VR) for molecular toxicology. We modeled VR with the tricarboxylic acid (TCA) cycle, a major working mechanism of several toxic poisons such as fluoroacetate, malonate, arsenite, etc. to improve the effectiveness of education in molecular toxicology for better recall compared to traditional education methods.

Results

We devised an educational system and theoretical basis for virtual reality visualization model (VRVM), as integrated research in this area had been insufficient thus far. We found that VRVM has positive effects on learning and memory when teaching complex topics such as molecular toxicology in our previous study.

Conclusions

This study has three main components: (1) construction of VR hardware/software (HW/SW) system; (2) creation of VR space design guide; and (3) verification of VRVM spatiotemporality. Consequently, we developed VRVM for the TCA cycle of toxicological mechanism to improve the study habits of medical students in the context of molecular toxicology studies. To continuously expand this approach for future educational applications, up-to-date findings in areas such as cognitive neuroscience and psychology for studying molecular toxicology should be incorporated to strengthen concepts, logic, and physical models of visualization.

中文翻译：

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具有相对时空性的虚拟现实可视化模型（VRVM）的开发，用于分子毒理学教育中的视觉内容

背景

可视化教育内容使学习更加有效，尤其是在分子毒理学等领域，这既费时又费力地学习。

目的

开发了一种基于认知神经科学的设计原理，用于信息的时空性，并针对分子毒理学优化了虚拟现实（VR）。我们使用三羧酸（TCA）循环对VR进行了建模，该循环是多种有毒物质（例如氟乙酸盐，丙二酸盐，亚砷酸盐等）的主要工作机制，以提高分子毒理学教育的有效性，与传统的教育方法相比，具有更好的回忆性。

结果

我们设计了虚拟现实可视化模型（VRVM）的教育系统和理论基础，因为到目前为止该领域的综合研究还不够。我们发现，在我们先前的研究中，VRVM在教授诸如分子毒理学之类的复杂主题时，会对学习和记忆产生积极影响。

结论

这项研究包括三个主要部分：（1）VR硬件/软件（HW / SW）系统的构建；（2）创建VR空间设计指南；（3）验证VRVM的时空性。因此，我们开发了用于TCA周期毒理学机制的VRVM，以改善分子毒理学研究背景下医学生的学习习惯。为了将这种方法不断扩展以用于未来的教育应用，应该结合认知神经科学和心理学等领域的最新发现来研究分子毒理学，以加强可视化的概念，逻辑和物理模型。