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tANCHOR: a novel mammalian cell surface peptide display system.
Biotechniques ( IF 2.2 ) Pub Date : 2020-12-14 , DOI: 10.2144/btn-2020-0073
Daniel Ivanusic 1 , Kazimierz Madela 2 , Heidi Burghard 1 , Gudrun Holland 2 , Michael Laue 2 , Norbert Bannert 1
Affiliation  

A novel tool for the presentation of peptides and small proteins on the surface of human cells has been developed. Our tANCHOR system utilizes tetraspanin anchors containing heterologous amino acid sequences inserted instead of the large extracellular loop. This technology allows a highly effective extracellular display of epitopes for antibody binding studies and many other potential applications.

中文翻译:

tANCHOR:一种新型哺乳动物细胞表面肽展示系统。

已经开发出一种用于在人类细胞表面呈递肽和小蛋白的新工具。我们的 tANCHOR 系统利用包含插入的异源氨基酸序列而不是大细胞外环的四跨膜锚定。该技术允许高效的细胞外表位展示,用于抗体结合研究和许多其他潜在应用。
更新日期:2020-12-16
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