ABSTRACT

The aim of this study was to analyze the influence of reproductive aging on executive functions. We assessed executive functions in three groups of healthy women in the premenopausal (n = 45, mean age = 30.89, SD = 10.5), perimenopausal (n = 31, mean age = 50.06, SD = 3.6) and postmenopausal (n = 24, mean age = 63.39, SD = 6.5) phase. No differences between groups were observed in working memory, verbal fluency, inhibitory control, planning, and cognitive flexibility. However, when the analyses were repeated with participants with occupations with lower intellectual demands, perimenopausal and postmenopausal women performed worse than premenopausal women in semantic verbal fluency. This study provides important evidence to understand the effects of reproductive aging on cognitive performance in healthy women. Our findings indicate that cognitive reserve-related factors may be important to understand the differences in executive functions associated with reproductive aging.

摘要

本研究的目的是分析生殖衰老对执行功能的影响。我们评估了三组健康女性在绝经前（n = 45，平均年龄 = 30.89，SD = 10.5）、围绝经期（n = 31，平均年龄 = 50.06，SD = 3.6）和绝经后（n = 24，平均年龄 = 63.39，SD = 6.5) 阶段。在工作记忆、语言流利度、抑制控制、计划和认知灵活性方面没有观察到组间差异。然而，当对智力要求较低的职业的参与者重复分析时，围绝经期和绝经后女性在语义语言流利度方面的表现比绝经前女性差。这项研究为了解生殖衰老对健康女性认知能力的影响提供了重要证据。