Metagenomic next-generation sequencing (mNGS) is an emerging sequence-based method that detects genomic information of pathogenic microorganisms from a wide range of clinical specimens. The mNGS has moderate sensitivity and very high specificity for tuberculous meningitis, and the validity of mNGS was higher than that of Xpert MTB/RIF.

中文翻译：

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宏基因组二代测序与Xpert MTB/RIF在结核性脑膜炎诊断中的疗效比较

宏基因组二代测序（mNGS）是一种新兴的基于序列的方法，可从广泛的临床标本中检测病原微生物的基因组信息。mNGS对结核性脑膜炎具有中等敏感性和极高特异性，mNGS的有效性高于Xpert MTB/RIF。