From a perspective of drug administration, eco-pharmacovigilance (EPV) has been proposed as a new approach to prevent the environmental risks posed by pharmaceutical emerging contaminants. However, it is impracticable to practice unitary and rigor EPV process for all the pharmaceutical substances with complex and diversified chemical, biological or toxicological properties. We proposed the “targeted EPV” that is the science and activities associated with the targeted detection, evaluation, understanding, and prevention of adverse effects of high-priority hazardous pharmaceuticals in the environment, especially focusing on the control of main anthropogenic sources of pharmaceutical emission among key stakeholders in high-risk areas could be used as an optimized management strategy for pharmaceutical pollution. “Targeted EPV” implementation should focus on the targeted monitoring of the occurrence of high-priority pharmaceuticals in environmental samples, the targeted reporting of over-standard discharge, the targeted management for main emission sources, the targeted legislation and researches on high-priority pharmaceutical pollutants, as well as the targeted educational strategies for specific key populations.

从药物管理的角度来看，已经提出了生态药物警戒（EPV）作为一种预防新出现的药物造成的环境风险的新方法。但是，对所有具有复杂和多样化的化学，生物学或毒理学特性的药物进行统一而严格的EPV处理是不可行的。我们提出了“有针对性的EPV”，即与目标检测，评估，理解和预防环境中高优先级危险药物的不良反应相关的科学和活动，特别是着重于控制主要的人为排放源在高风险地区的关键利益相关者中，可以将其用作药物污染的优化管理策略。