The application of monolithic materials as carriers for enzymes has rapidly expanded to the realization of flow-through analysis and bioconversion processes. This expansion is partly attributed to the absence from diffusion limitation in many monoliths-based enzyme reactors. Particularly, the relatively ease of introducing functional groups renders polymer monoliths attractive as enzyme carriers. After summarizing the motivation to develop enzymatic reactors using polymer monoliths, this review reports the most recent applications of such reactors. Besides, the present review focuses on the crucial characteristics of polymer monoliths affecting the immobilization of enzymes and the processing parameters dictating the performance of the resulting enzymatic reactors. This review is intended to provide a guideline for designing and applying flow-through enzymatic reactors using polymer monoliths.

中文翻译：

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使用聚合物整料的流通式酶反应器：从动机到应用

整体材料作为酶载体的应用已迅速扩展到流通分析和生物转化过程的实现。这种扩展部分归因于许多基于整体的酶反应器中没有扩散限制。特别是，引入官能团的相对容易性使得聚合物单块作为酶载体具有吸引力。在总结了使用聚合物单块开发酶反应器的动机后，本综述报告了此类反应器的最新应用。此外，本综述重点关注影响酶固定的聚合物单体的关键特性以及决定酶反应器性能的工艺参数。