Endothelium‐derived hyperpolarization (EDH)‐mediated response plays an essential role in the control of kidney preglomerular circulation, but the identity of the K⁺ channels involved in this response is still controversial. We hypothesized that large‐ (K_Ca1.1), intermediate‐ (K_Ca3.1) and small (K_Ca2.3) ‐conductance Ca²⁺‐activated K⁺ (K_Ca) channels are expressed in the endothelium of the preglomerular circulation and participate in the EDH‐mediated response.

中文翻译：

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内皮 KCa1.1 和 KCa3.1 通道介导大鼠肾动脉内皮源性超极化反应

内皮源性超极化 (EDH) 介导的反应在控制肾小球前循环中起重要作用，但参与该反应的 K ⁺通道的身份仍存在争议。我们假设大 (K _Ca 1.1)、中 (K _Ca 3.1) 和小 (K _Ca 2.3) 电导 Ca ²⁺激活的 K ⁺ (K _Ca ) 通道在肾小球前循环的内皮中表达并参与在 EDH 介导的反应中。