The appeal of using microbial inoculants to mediate plant traits and productivity in managed ecosystems has increased over the past decade, because microbes represent an alternative to fertilizers, pesticides, and direct genetic modification of plants. Using microbes bypasses many societal and environmental concerns because microbial products are considered a more sustainable and benign technology. In our desire to harness the power of plant–microbial symbioses, are we ignoring the possibility of precipitating microbial invasions, potentially setting ourselves up for a microbial Jurassic Park? Here, we outline potential negative consequences of microbial invasions and describe a set of practices (Testing, Regulation, Engineering, and Eradication, TREE) based on the four stages of invasion to prevent microbial inoculants from becoming invasive. We aim to stimulate discussion about best practices to proactively prevent microbial invasions.

在过去的十年中，使用微生物接种剂调节受管理生态系统中的植物性状和生产力的吸引力有所增加，因为微生物代表了肥料、杀虫剂和植物直接基因改造的替代品。使用微生物可以绕过许多社会和环境问题，因为微生物产品被认为是一种更具可持续性和良性的技术。在我们希望利用植物-微生物共生的力量的过程中，我们是否忽略了促进微生物入侵的可能性，从而可能为微生物侏罗纪公园做好准备？在这里，我们概述了微生物入侵的潜在负面后果，并根据入侵的四个阶段描述了一组实践（测试、监管、工程和根除，树），以防止微生物接种剂成为入侵。