Background:Repetition of motor imagery improves the motor function of patients with stroke. However, patients who develop severe upper-limb paralysis after chronic stroke often have an impaired ability to induce motor imagery. We have developed a method to passively induce kinesthetic perception using visual stimulation (kinesthetic illusion induced by visual stimulation [KINVIS]). Objective:This pilot study further investigated the effectiveness of KINVIS in improving the induction of kinesthetic motor imagery in patients with severe upper-limb paralysis after stroke. Methods:Twenty participants (11 with right hemiplegia and 9 with left hemiplegia; mean time from onset [±standard deviation], 67.0±57.2 months) with severe upper-limb paralysis who could not extend their paretic fingers were included in this study. The ability to induce motor imagery was evaluated using the event-related desynchronization (ERD) recorded during motor imagery before and after the application of KINVIS for 20 min. The alpha- and beta-band ERDs around the premotor, primary sensorimotor, and posterior parietal cortices of the affected and unaffected hemispheres were evaluated during kinesthetic motor imagery of finger extension and before and after the intervention. Results: Beta-band ERD recorded from the affected hemisphere around the sensorimotor area showed a significant increase after the intervention, while the other ERDs remained unchanged. Conclusions:In patients with chronic stroke who were unable to extend their paretic fingers for a prolonged period of time, the application of KINVIS, which evokes kinesthetic perception, improved their ability to induce motor imagery. Our findings suggest that although KINVIS is a passive intervention, its short-term application can induce changes related to the motor output system.

中文翻译：

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视觉刺激引起的动觉错觉影响严重上肢瘫痪的中风患者的感觉运动事件相关的不同步：一项初步研究

背景：重复运动意象可改善卒中患者的运动功能。然而，慢性中风后出现严重上肢瘫痪的患者通常具有诱发运动意象的能力受损。我们开发了一种使用视觉刺激（视觉刺激引起的动觉错觉 [KINVIS]）被动诱导动觉知觉的方法。目的：这项初步研究进一步调查了 KINVIS 在改善中风后严重上肢瘫痪患者动觉运动意象诱导方面的有效性。方法： 20 名患有严重上肢瘫痪且无法伸展麻痹手指的参与者（11 名右侧偏瘫和 9 名左侧偏瘫患者；从发病开始的平均时间 [±标准差]，67.0±57.2 个月）被纳入本研究。使用在应用 KINVIS 20 分钟之前和之后的运动想象过程中记录的事件相关去同步化 (ERD) 来评估诱发运动想象的能力。在手指伸展的动觉运动成像期间以及干预前后，评估了受影响和未受影响半球的前运动、初级感觉运动和后顶叶皮质周围的 α 和 β 波段 ERD。结果：从感觉运动区周围受影响的半球记录的 Beta 波段 ERD 在干预后显示出显着增加，而其他 ERD 保持不变。结论：对于长时间无法伸展麻痹手指的慢性脑卒中患者，应用KINVIS唤起动觉知觉，提高了他们诱发运动意象的能力。