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Augmentation of core decompression with synthetic bone graft does not improve mechanical properties of the proximal femur
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.3 ) Pub Date : 2020-12-11 , DOI: 10.1016/j.jmbbm.2020.104263
Samuel A Hockett 1 , John T Sherrill 2 , Micah Self 2 , Simon C Mears 2 , C Lowry Barnes 2 , Erin M Mannen 3
Affiliation  

Core decompression is a minimally invasive surgical technique used to treat patients with avascular necrosis of the femoral head. The procedure requires an entry hole in the lateral cortex of the femur which potentially leaves patients susceptible to subtrochanteric fractures. The purpose of this study was to determine if filling the core decompression tract with synthetic bone-graft mechanically strengthens the proximal femur. Twenty composite synthetic femurs underwent a core decompression procedure; ten were augmented with synthetic bone-graft (PRO-DENSE™, Wright Medical) and ten femurs were left unfilled as a control group. Compressive testing to failure was performed using a mechanical testing machine. Stiffness, fracture load, and toughness did not significantly differ between groups. More subtrochanteric fractures were seen in the control group (6 of 10 specimens) compared to the bone-graft augmented group (2 of 10 specimens). In conclusion, augmentation of a core decompression tract does not improve mechanical properties in a synthetic bone model but may be protective of subtrochanteric fracture.



中文翻译:

用合成骨移植增强核心减压并不能改善股骨近端的机械性能

髓芯减压术是一种微创手术技术,用于治疗股骨头缺血性坏死患者。该手术需要在股骨外侧皮层有一个入口孔,这可能会使患者容易发生转子下骨折。本研究的目的是确定用合成骨移植物填充核心减压道是否会机械地增强股骨近端。20 根复合合成股骨进行了核心减压手术;十个用合成骨移植物(PRO-DENSE™,Wright Medical)增强,十个股骨未填充作为对照组。使用机械试验机进行压缩失效测试。各组之间的刚度、断裂载荷和韧性没有显着差异。与骨移植增强组(10 个样本中的 2 个)相比,对照组(10 个样本中的 6 个)出现更多的转子下骨折。总之,核心减压道的增强不会改善合成骨模型的机械性能,但可能会保护转子下骨折。

更新日期:2020-12-29
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