ABSTRACT

Introduction: Fibromyalgia represents the most prevalent of the group of conditions that are known as central sensitivity syndromes. Approximately 2–5% of the adult population in the United States is affected by Fibromyalgia. This pain amplification syndrome has an enormous economic impact as measured by work absenteeism, decreased work productivity, disability and injury compensation, and over-utilization of healthcare resources. Multiple studies have shown that early diagnosis of this condition can improve patient outlook, and redirect valuable health care resources toward more appropriate targeted therapy. Efforts have been made toward improving diagnostic accuracy through updated criteria.

Areas Covered: Reviewed here are 1) reasons for the need for more accurate diagnosis of Fibromyalgia, (2) a review of the evolution of Fibromyalgia to current times, and (3) the proliferation of currently available diagnostic criteria and problems related to each of them. From initial literature review until October 2020, PubMed, Embase, and Scopus were searched for applicable literature.

Expert Opinion: A discussion of ongoing efforts to obtain a biomarker to enhance diagnostic accuracy concludes this review. A need to include rheumatologists as part of the care team of patients with Fibromyalgia is emphasized.

摘要

简介：纤维肌痛是被称为中枢敏感性综合症的一组病症中最普遍的一种。在美国，大约2–5％的成年人口患有纤维肌痛。通过缺勤，工作生产率下降，残疾和伤害补偿以及医疗资源的过度利用，这种疼痛放大综合症具有巨大的经济影响。多项研究表明，对此病的早期诊断可以改善患者的视线，并将宝贵的医疗资源重定向到更合适的靶向治疗上。已经努力通过更新的标准来提高诊断准确性。

涵盖的领域：这里审查有1）需要更准确地诊断纤维肌痛的原因，（2）回顾了纤维肌痛到近代的演变，以及（3）当前可用的诊断标准的扩散以及与每一个相关的问题他们。从最初的文献审阅到2020年10月，在PubMed，Embase和Scopus进行搜索以寻找适用的文献。

专家意见：对正在进行的旨在获得生物标志物以提高诊断准确性的工作的讨论得出了此结论。强调需要将风湿病医师纳入纤维肌痛患者护理团队。