Human transformation of natural habitats facilitates pathogen transmission between domestic and wild species. The guigna (Leopardus guigna), a small felid found in Chile, has experienced habitat loss and an increased probability of contact with domestic cats. Here, we describe the interspecific transmission of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) between domestic cats and guignas and assess its correlation with human landscape perturbation. Blood and tissue samples from 102 free‐ranging guignas and 262 domestic cats were collected and analyzed by PCR and sequencing. Guigna and domestic cat FeLV and FIV prevalence were very similar. Phylogenetic analysis showed guigna FeLV and FIV sequences are positioned within worldwide domestic cat virus clades with high nucleotide similarity. Guigna FeLV infection was significantly associated with fragmented landscapes with resident domestic cats. There was little evidence of clinical signs of disease in guignas. Our results contribute to the understanding of the implications of landscape perturbation and emerging diseases.

中文翻译：

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智利人类居住地区的家养猫科动物和野生猫科动物之间逆转录病毒的跨物种传播


人类对自然栖息地的改造促进了病原体在驯养物种和野生物种之间的传播。吉尼亚猫（ Leopardus guigna ）是在智利发现的一种小型猫科动物，它的栖息地丧失，与家猫接触的可能性增加。在这里，我们描述了猫白血病病毒（FeLV）和猫免疫缺陷病毒（FIV）在家猫和吉尼亚斯之间的种间传播，并评估其与人类景观扰动的相关性。收集了 102 只自由放养的吉尼亚猫和 262 只家猫的血液和组织样本，并通过 PCR 和测序进行分析。 Guigna 和家猫 FeLV 和 FIV 的患病率非常相似。系统发育分析显示 guigna FeLV 和 FIV 序列位于全球家猫病毒进化枝内，具有高度的核苷酸相似性。 Guigna FeLV 感染与居住的家猫的破碎景观显着相关。几乎没有证据表明吉尼亚斯有疾病的临床症状。我们的结果有助于理解景观扰动和新出现疾病的影响。