When esophageal acid exposure time (AET) is physiologic, ROME IV stratifies functional esophageal disorders into functional heartburn (FH, with negative reflux-symptom association) and reflux hypersensitivity (RH, with positive reflux-symptom association), and hypothesizes that FH/RH could overlap with proven gastroesophageal reflux disease (GERD). We compared conventional FH/RH diagnosed off antisecretory therapy with overlap FH/RH coexisting with proven GERD.

中文翻译：

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功能性胃灼热和反流超敏反应与已证实的胃食管反流病重叠

当食管酸暴露时间 (AET) 是生理性的时，ROME IV 将功能性食管疾病分为功能性胃灼热（FH，与反流-症状相关性负相关）和反流超敏反应（RH，与反流-症状相关性相关），并假设 FH/RH可能与已证实的胃食管反流病 (GERD) 重叠。我们比较了常规 FH/RH 诊断为停用抗分泌治疗与重叠 FH/RH 与已证实的 GERD 并存。