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Condensed internet-delivered prolonged exposure provided soon after trauma: A randomised pilot trial
Internet Interventions ( IF 3.6 ) Pub Date : 2020-12-10 , DOI: 10.1016/j.invent.2020.100358
Maria Bragesjö , Filip K. Arnberg , Josefin Särnholm , Klara Olofsdotter Lauri , Erik Andersson

Exposure to trauma is common and may have detrimental psychological consequences. Brief exposure therapy provided early after trauma has shown encouraging results in promoting recovery. To scale up treatment availability, we developed a 3-week internet-delivered intervention comprised of four modules based on prolonged exposure (condensed internet-delivered prolonged exposure; CIPE) with therapist support. In this pilot study, we assessed the feasibility, acceptability, and preliminary efficacy of CIPE delivered within 2 months after the index event. Thirty-three participants were randomised to CIPE or a waiting list (WL). The frequency, vividness and distress of intrusive recollections or flashback memories of the traumatic event were assessed using an intrusive memory smartphone app. Symptoms of post-traumatic stress were assessed by the PTSD Symptom Checklist for DSM-5 (PCL-5). The most common index traumas in the sample were rape, interpersonal violence and life-threatening accidents. A majority of participants (82%) randomised to CIPE completed all modules, and the number of logins per participant to the Internet platform was high during the three-week intervention (M = 19.6, SD = 11.8). At post-treatment, the CIPE participants had a more favourable reduction than the WL group on the vividness and distress ratings, as well as on the PCL-5 sum score (bootstrapped d = 0.85; 95% CI [0.25–1.45]). Treatment effects were sustained at 6-months follow up and no severe adverse events associated with the intervention were found. CIPE seems to be a feasible and possibly efficacious early intervention after trauma. Large-scale trials are needed to assess its efficacy and long-term benefits.



中文翻译:

创伤后不久就提供了由互联网提供的浓缩的长时间暴露:一项随机试验

遭受外伤是很常见的,可能会带来不利的心理后果。创伤后早期提供的简短暴露疗法在促进康复方面显示出令人鼓舞的结果。为了扩大治疗的可获得性,我们在治疗师的支持下,根据延长的暴露时间(浓缩的互联网提供的长期暴露; CIPE),开发了一个为期3周的由互联网提供的干预措施,包括四个模块。在这项初步研究中,我们评估了指数事件后2个月内交付CIPE的可行性,可接受性和初步疗效。33名参与者被随机分配至CIPE或候补名单(WL)。使用侵入式记忆智能手机应用程序评估创伤事件的侵入式回忆或闪回记忆的频率,生动度和困扰。创伤后应激反应的症状通过PTSD DSM-5症状检查表(PCL-5)进行评估。样本中最常见的指数创伤是强奸,人际暴力和威胁生命的事故。随机分配到CIPE的大多数参与者(82%)完成了所有模块,在为期三周的干预期间,每个参与者登录Internet平台的次数都很高(M  = 19.6,SD  = 11.8)。在后处理时,CIPE参与者有更有利的减少比在鲜艳度和苦恼评级WL组,以及在PCL-5和评分(自举d  = 0.85; 95%CI [0.25-1.45])。在随访6个月后,治疗效果得以维持,未发现与干预措施相关的严重不良事件。CIPE似乎是创伤后的可行且可能有效的早期干预措施。需要进行大规模试验来评估其疗效和长期获益。

更新日期:2020-12-23
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