Abstract

This study demonstrates the applications of Bacillus coagulans in alcohol elimination. Bacillus coagulans has recently drawn tremendous interest in the food industry and medicine considering its great environmental tolerance and beneficial effects on improving gastrointestinal diseases. However, few scientific reports connect its utilities with alcohol elimination. In this study, we introduced the unique strain B. coagulans TCI711 for such exploration. TCI711 contained alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) by mass spectrum and resisted gastric acid and bile acid. Also, taking TCI711 capsules for a week can significantly improve alcohol metabolism in humans (breath alcohol level indicated 0 mg/kg in 2 h after drinking 75 mL of whisky). In brief, this exploratory research unveiled the potent applications of B. coagulans in alcohol elimination in humans.

摘要

这项研究表明凝结芽孢杆菌在消除酒精中的应用。凝结芽孢杆菌最近对食品工业和医学引起了极大的兴趣，因为它对环境的耐受力强，并且对改善胃肠道疾病具有有益作用。但是，很少有科学报告将其实用性与消除酒精联系起来。在这项研究中，我们介绍了独特的菌株凝结芽孢杆菌TCI711适用于此类探索。TCI711质谱图中包含乙醇脱氢酶（ADH）和醛脱氢酶（ALDH），并具有抗胃酸和胆汁酸的能力。同样，服用TCI711胶囊一周可以显着改善人类的酒精代谢（饮用75 mL威士忌后2小时内呼吸酒精水平指示为0 mg / kg）。简而言之，这项探索性研究揭示了凝结芽孢杆菌在人类消除酒精中的有效应用。