One-pot four component synthesis of 2,5,6-triaryl pyrazines, 1,2,4,5-tetraaryl imidazoles and 2,2,4,5-tetraaryl imidazoles have been achieved from benzoin, aryl amine, ammonium acetate and aryl ketone /aryl aldehydes using lemon juice (Citrus limon) as an ecofriendly catalyst in good yield under mild conditions. The antibacterial action exhibited by the synthesized compounds against clinical isolates obtained from urinary tract catheters of infected patients is close to the standard drug tetracycline. Recovery of lemon juice after completion of reaction eliminates the need to handle side products, making this process more safe and user friendly.

中文翻译：

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以柠檬汁（柠檬柠檬）为可回收催化剂合成吡嗪和咪唑

由安息香，芳基胺，乙酸铵和芳基可实现一锅四组分合成2,5,6-三芳基吡嗪，1,2,4,5-四芳基咪唑和2,2,4,5-四芳基咪唑使用柠檬汁（Citrus limon）作为生态友好型催化剂的酮/芳基醛，在温和的条件下具有良好的收率。合成的化合物对从感染患者的尿道导管获得的临床分离株表现出的抗菌作用接近标准药物四环素。反应完成后回收柠檬汁，无需再处理副产品，从而使该过程更加安全和用户友好。