Background: Colorectal cancer (CRC) rates are affected by genetics, ethnicity, and environmental factors; it is considered one of the most aggressive human malignancies with high mortality and morbidity rates worldwide due, in part, to its asymptomatic nature during the early stages of disease.

中文翻译：

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miR-21，miR-23a和miR-27a的差异表达及其在埃及大肠癌患者中的诊断意义

背景：大肠癌的发病率受遗传，种族和环境因素的影响。它被认为是世界范围内具有最高死亡率和发病率的最具侵略性的人类恶性肿瘤之一，部分原因是其在疾病早期具有无症状的性质。